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     Shenzhen OK Biotech Technology Co., Ltd.(SZOB)

     HK Add: 6/F, Fo Tan Industrial Centre, 26-28 Au Pui Wan St ,Fo Tan, Shatin, Hongkong

     China mainland Add: 8F, Fuxuan Building, No. 46, East Heping Rd, Longhua New  District,  Shenzhen, PRC China

     Email: nicole@ok-biotech.com

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     Tel: +852 6679 4580

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Tamoxifen Citrate, 54965-24-1, Steriods And Hormone

Edit: Shenzhen OK Biotech Technology Co., Ltd. (SZOB)    Date: Aug 27, 2015

Breast Cancer Health Center--Tamoxifen Citrate, 54965-24-1


Use in Cancer

Tamoxifen citrate 54965-24-1 is approved to treat:

Breast cancer in women and men.

Tamoxifen citrate 54965-24-1 is also approved to prevent:

Breast cancer in women who are at high risk for the disease.

Tamoxifen citrate 54965-24-1 is also being studied in the treatment of other types of cancer.

The citrate salt of an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). Tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. In addition, tamoxifen up-regulates the production of transforming growth factor B (TGFb), a factor that inhibits tumor cell growth, and down-regulates insulin-like growth factor 1 (IGF-1), a factor that stimulates breast cancer cell growth. Tamoxifen 54965-24-1 also down-regulates protein kinase C (PKC) expression in a dose-dependant manner, inhibiting signal transduction and producing an antiproliferative effect in tumors such as malignant glioma and other cancers that overexpress PKC. Check for active clinical trials using this agent. (NCI Thesaurus)



Breast Cancer: Treatment by Stage


Stage 1 Breast Cancer Treatment Options-Tamoxifen Citrate, 54965-24-1

In Stage 1 breast cancer, the cancer is still considered in an early stage. Learn about its treatment options.

Stage 2 Breast Cancer Treatment Options-Tamoxifen Citrate, 54965-24-1

In stage 2 breast cancer, the cancer is in the breast and may also be in nearby lymph nodes. This article describes Stage 2 breast cancer treatment options.


Stage 3 Breast Cancer Treatment Options-Tamoxifen Citrate, 54965-24-1

In stage 3 breast cancer, cancer hasn’t spread far beyond the breast and nearby lymph nodes. Read about its treatment options.


Stage 4 Breast Cancer Treatment Options-Tamoxifen Citrate, 54965-24-1

Stage 4 breast cancer has spread beyond the breast and nearby lymph nodes to other parts of the body. Learn how it’s treated.


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Address: HK: 6/F,Fo Tan Industrial Centre,26-28 Au Pui Wan St,Fo Tan,Shatin,Hongkong Shenzhen: 8F, Fuxuan Building, No. 46, East Heping Rd, Longhua New District, Shenzhen, PRC China
Tel: +852 6679 4580
 Fax:+852 6679 4580
 E-mail:smile@ok-biotech.com
Shenzhen OK Biotech Technology Co., Ltd.(SZOB)
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