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Mifepristone, CAS 84371-65-3



Mifepristone, CAS 84371-65-3


Basic information

Product Name: Mifepristone

Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486

CAS: 84371-65-3

MF: C29H35NO2

MW: 429.59

EINECS:

Product Categories: Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone Drugs

Mol File: 84371-65-3.mol

Mifepristone Structure

Mifepristone Chemical Properties

mp 195-198°C

storage temp. 2-8°C

Merck 6186

CAS DataBase Reference 84371-65-3(CAS DataBase Reference)

Safety Information

Hazard Codes T

Risk Statements 60-61

Safety Statements 53-22-36/37/39-45

WGK Germany 3

RTECS KG2955000

Hazardous Substances Data 84371-65-3(Hazardous Substances Data)

MSDS Information

Provider Language

11b-[p-(Dimethylamino)phenyl]-17b-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one English

SigmaAldrich English

Mifepristone Usage And Synthesis

Chemical Properties Pale Yellow Solid

Usage A progesterone receptor antagonist with partial agonist activity. Abortifacient.

Usage glutamate uptake inhibitor, AMPA blocker

Biological Activity Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro and in vivo . Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone.

Mifepristone Preparation Products And Raw materials

Raw materials Tetrahydrofuran-->N,N-Dimethylaniline-->Isopropyl ether-->Dimethyl sulfide


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