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Anastrozole, CAS 120511-73-1

Anastrozole, CAS 120511-73-1

Basic information

Product Name:Anastrozole

Synonyms:ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t





Product Categories:Active Pharmaceutical Ingredients;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Anastrozole;API

Mol File:120511-73-1.mol

Anastrozole Structure

Anastrozole Chemical Properties

mp 81-82°C

storage temp. Store at RT

CAS DataBase Reference120511-73-1(CAS DataBase Reference)

Safety Information

Hazard Codes Xi,Xn

Risk Statements 36/37/38-22-61-60

Safety Statements 26-37/39


HazardClass 6.1(b)

PackingGroup III

HS Code 29339980

Hazardous Substances Data120511-73-1(Hazardous Substances Data)

MSDS Information



Anastrozole Usage And Synthesis

Chemical PropertiesCrystalline Solid

UsageAn aromatase inhibitor. Used as an antineoplastic.

Usageantiseptic, spermaticide

Biological ActivityPotent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active.

Anastrozole Preparation Products And Raw materials

Raw materialsEthyl acetate-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Sodium hydride -->Carbon tetrachloride-->Iodomethane-->N-Bromosuccinimide-->1,2,4-Triazole-->1,2,4-Triazolylsodium-->5-Methyl-1,3-benzenediacetonitrile

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