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Anastrozole

Edit: Shenzhen OK Biotech Technology Co., Ltd. (SZOB)    Date: Aug 19, 2016

Anastrozole

Anastrozole CAS: 120511-73-1

What is anastrozole?


Anastrozole is a prescription drug. It’s available as an oral tablet.


Anastrozole is available as a generic tablet. Generic drugs usually cost less. 

In some cases they may not be available in the same strengths or dosage forms as the brand. 

Talk to your healthcare provider to see if the generic will work for you.


This drug may be used with other medications to treat breast cancer..


Why it is used?

Anastrozole is used to treat breast cancer. It’s given to women who have gone through menopause (postmenopausal). 

Specifically, it’s used for:


1. treatment of early breast cancer. It’s given to women with hormone receptor-positive or unknown breast cancer after surgery or in addition to other therapies.

2. initial or first treatment of breast cancer that’s spread to other parts of the body (metastasized). 

It’s used in women with hormone receptor-positive breast cancer or when the hormone receptors aren’t known.

3. treatment of advanced breast cancer. It’s given when your disease has progressed, even after early response with the cancer drug tamoxifen.


Anastrozole doesn’t work well in women with estrogen receptor-negative breast cancer or in those who didn’t respond to their tamoxifen treatment at all.



How it works?

Anastrozole belongs to a class of drugs called aromatase inhibitors. 

They block the production of estrogen—a key stimulator of breast cancer. 

A class of drugs refers to medications that work similarly. 

They have a similar chemical structure and are often used to treat similar conditions.


In postmenopausal women, aromatase, an enzyme, changes hormones called androgens into the hormone estrogen. 

Many breast cancer tumors grow when estrogen is present. Anastrozole stops aromatase from working. 

This lowers the amount of the potentially cancer-causing estrogen in your body and in the cancer tissue.

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